Next-generation sequencing technologies have enhanced the scope of Internet-of-Things (IoT) to include genomics for personalized medicine through the increased availability of an abundance of genome data collected from heterogeneous sources at a reduced cost. Given the sheer magnitude of the collected data and the significant challenges offered by the presence of highly similar genomic structure across species, there is a need for robust, scalable analysis platforms to extract actionable knowledge such as the presence of potentially zoonotic pathogens. The emergence of zoonotic diseases from novel pathogens, such as the influenza virus in 1918 and SARS-CoV-2 in 2019 that can jump species barriers and lead to pandemic underscores the need for scalable metagenome analysis. In this work, we propose MG2Vec, a deep learning-based solution that uses the transformer network as its backbone, to learn robust features from raw metagenome sequences for downstream biomedical tasks such as targeted and generalized pathogen detection. Extensive experiments on four increasingly challenging, yet realistic diagnostic settings, show that the proposed approach can help detect pathogens from uncurated, real-world clinical samples with minimal human supervision in the form of labels. Further, we demonstrate that the learned representations can generalize to completely unrelated pathogens across diseases and species for large-scale metagenome analysis. We provide a comprehensive evaluation of a novel representation learning framework for metagenome-based disease diagnostics with deep learning and provide a way forward for extracting and using robust vector representations from low-cost next generation sequencing to develop generalizable diagnostic tools.

Scene graphs provide a rich, structured representation of a scene by encoding the entities (objects) and their spatial relationships in a graphical format. This representation has proven useful in several tasks, such as question answering, captioning, and even object detection, to name a few. Current approaches take a generation-by-classification approach where the scene graph is generated through labeling of all possible edges between objects in a scene, which adds computational overhead to the approach. This work introduces a generative transformer-based approach to generating scene graphs beyond link prediction. Using two transformer-based components, we first sample a possible scene graph structure from detected objects and their visual features. We then perform predicate classification on the sampled edges to generate the final scene graph. This approach allows us to efficiently generate scene graphs from images with minimal inference overhead. Extensive experiments on the Visual Genome dataset demonstrate the efficiency of the proposed approach. Without bells and whistles, we obtain, on average, 20.7% mean recall (mR@100) across different settings for scene graph generation (SGG), outperforming state-of-the-art SGG approaches while offering competitive performance to unbiased SGG approaches.

视觉事件的感知任务，如动作定位主要集中在静态观察者下的监督学习设置，即，相机是静态的，不能通过算法控制。它们通常受到\ Texit {Annotated}培训数据的质量，数量和多样性，并且通常不会概括为域外样本。在这项工作中，我们解决了主动动作本地化的问题，其中目标是在控制活动摄像机的几何和物理参数时本地化一个动作，以便在不训练数据的情况下在视野中保持动作。我们制定了一种基于能量的机制，将预测学习和反应性控制结合到没有奖励的无需奖励的主动动作定位，这可以在现实世界环境中稀疏或不存在。我们在两个任务上对模拟和现实世界的环境进行了广泛的实验 - 活动对象跟踪和主动操作本地化。我们展示了所提出的方法可以以媒体方式以不同的任务和环境概括，而无明确的奖励或培训。我们表明，拟议的方法优于未经监督的基线，与培训具有加强学习的人相比，获得竞争性能。

Event perception tasks such as recognizing and localizing actions in streaming videos are essential for scaling to real-world application contexts. We tackle the problem of learning actor-centered representations through the notion of continual hierarchical predictive learning to localize actions in streaming videos without the need for training labels and outlines for the objects in the video. We propose a framework driven by the notion of hierarchical predictive learning to construct actor-centered features by attention-based contextualization. The key idea is that predictable features or objects do not attract attention and hence do not contribute to the action of interest. Experiments on three benchmark datasets show that the approach can learn robust representations for localizing actions using only one epoch of training, i.e., a single pass through the streaming video. We show that the proposed approach outperforms unsupervised and weakly supervised baselines while offering competitive performance to fully supervised approaches. Additionally, we extend the model to multi-actor settings to recognize group activities while localizing the multiple, plausible actors. We also show that it generalizes to out-of-domain data with limited performance degradation.

While the brain connectivity network can inform the understanding and diagnosis of developmental dyslexia, its cause-effect relationships have not yet enough been examined. Employing electroencephalography signals and band-limited white noise stimulus at 4.8 Hz (prosodic-syllabic frequency), we measure the phase Granger causalities among channels to identify differences between dyslexic learners and controls, thereby proposing a method to calculate directional connectivity. As causal relationships run in both directions, we explore three scenarios, namely channels' activity as sources, as sinks, and in total. Our proposed method can be used for both classification and exploratory analysis. In all scenarios, we find confirmation of the established right-lateralized Theta sampling network anomaly, in line with the temporal sampling framework's assumption of oscillatory differences in the Theta and Gamma bands. Further, we show that this anomaly primarily occurs in the causal relationships of channels acting as sinks, where it is significantly more pronounced than when only total activity is observed. In the sink scenario, our classifier obtains 0.84 and 0.88 accuracy and 0.87 and 0.93 AUC for the Theta and Gamma bands, respectively.

Differentiable Architecture Search (DARTS) has attracted considerable attention as a gradient-based Neural Architecture Search (NAS) method. Since the introduction of DARTS, there has been little work done on adapting the action space based on state-of-art architecture design principles for CNNs. In this work, we aim to address this gap by incrementally augmenting the DARTS search space with micro-design changes inspired by ConvNeXt and studying the trade-off between accuracy, evaluation layer count, and computational cost. To this end, we introduce the Pseudo-Inverted Bottleneck conv block intending to reduce the computational footprint of the inverted bottleneck block proposed in ConvNeXt. Our proposed architecture is much less sensitive to evaluation layer count and outperforms a DARTS network with similar size significantly, at layer counts as small as 2. Furthermore, with less layers, not only does it achieve higher accuracy with lower GMACs and parameter count, GradCAM comparisons show that our network is able to better detect distinctive features of target objects compared to DARTS.

We propose an ensemble approach to predict the labels in linear programming word problems. The entity identification and the meaning representation are two types of tasks to be solved in the NL4Opt competition. We propose the ensembleCRF method to identify the named entities for the first task. We found that single models didn't improve for the given task in our analysis. A set of prediction models predict the entities. The generated results are combined to form a consensus result in the ensembleCRF method. We present an ensemble text generator to produce the representation sentences for the second task. We thought of dividing the problem into multiple small tasks due to the overflow in the output. A single model generates different representations based on the prompt. All the generated text is combined to form an ensemble and produce a mathematical meaning of a linear programming problem.

Diabetic Retinopathy (DR) is a leading cause of vision loss in the world, and early DR detection is necessary to prevent vision loss and support an appropriate treatment. In this work, we leverage interactive machine learning and introduce a joint learning framework, termed DRG-Net, to effectively learn both disease grading and multi-lesion segmentation. Our DRG-Net consists of two modules: (i) DRG-AI-System to classify DR Grading, localize lesion areas, and provide visual explanations; (ii) DRG-Expert-Interaction to receive feedback from user-expert and improve the DRG-AI-System. To deal with sparse data, we utilize transfer learning mechanisms to extract invariant feature representations by using Wasserstein distance and adversarial learning-based entropy minimization. Besides, we propose a novel attention strategy at both low- and high-level features to automatically select the most significant lesion information and provide explainable properties. In terms of human interaction, we further develop DRG-Net as a tool that enables expert users to correct the system's predictions, which may then be used to update the system as a whole. Moreover, thanks to the attention mechanism and loss functions constraint between lesion features and classification features, our approach can be robust given a certain level of noise in the feedback of users. We have benchmarked DRG-Net on the two largest DR datasets, i.e., IDRID and FGADR, and compared it to various state-of-the-art deep learning networks. In addition to outperforming other SOTA approaches, DRG-Net is effectively updated using user feedback, even in a weakly-supervised manner.

This paper deals with the problem of statistical and system heterogeneity in a cross-silo Federated Learning (FL) framework where there exist a limited number of Consumer Internet of Things (CIoT) devices in a smart building. We propose a novel Graph Signal Processing (GSP)-inspired aggregation rule based on graph filtering dubbed ``G-Fedfilt''. The proposed aggregator enables a structured flow of information based on the graph's topology. This behavior allows capturing the interconnection of CIoT devices and training domain-specific models. The embedded graph filter is equipped with a tunable parameter which enables a continuous trade-off between domain-agnostic and domain-specific FL. In the case of domain-agnostic, it forces G-Fedfilt to act similar to the conventional Federated Averaging (FedAvg) aggregation rule. The proposed G-Fedfilt also enables an intrinsic smooth clustering based on the graph connectivity without explicitly specified which further boosts the personalization of the models in the framework. In addition, the proposed scheme enjoys a communication-efficient time-scheduling to alleviate the system heterogeneity. This is accomplished by adaptively adjusting the amount of training data samples and sparsity of the models' gradients to reduce communication desynchronization and latency. Simulation results show that the proposed G-Fedfilt achieves up to $3.99\% $ better classification accuracy than the conventional FedAvg when concerning model personalization on the statistically heterogeneous local datasets, while it is capable of yielding up to $2.41\%$ higher accuracy than FedAvg in the case of testing the generalization of the models.

Previous work has shown the potential of deep learning to predict renal obstruction using kidney ultrasound images. However, these image-based classifiers have been trained with the goal of single-visit inference in mind. We compare methods from video action recognition (i.e. convolutional pooling, LSTM, TSM) to adapt single-visit convolutional models to handle multiple visit inference. We demonstrate that incorporating images from a patient's past hospital visits provides only a small benefit for the prediction of obstructive hydronephrosis. Therefore, inclusion of prior ultrasounds is beneficial, but prediction based on the latest ultrasound is sufficient for patient risk stratification.